Neuroinflammatory and Glutamatergic Dysregulation in Long COVID: Treating Brain Fog, Confusion, and Depression

John Murphy, – President, COVID-19 Long-haul Foundation Pathophysiology of Long COVID Neurocognitive Sequelae Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), is increasingly recognized as a chronic, multisystemic condition…[...]

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Long COVID and brain inflammation: unravelling mechanisms and potential therapies

Fatemeh Saheb Sharif-Askari1,2*†Jacob Raber3*†Karem H. Alzoubi1,2 Patients with Long COVID often experience persistent brain-related symptoms, including brain fog, mood changes, and dizziness (1–3), likely driven by neuroinflammation even after the…[...]

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Self-Reported Neuropsychiatric Post–COVID-19 Condition and CSF Markers of Neuroinflammation

Shelli F. Farhadian, MD, PhD1,2,3,4; Hailey D. Reisert, BS1; Lindsay McAlpine, MD3; et al, MA3,4 JAMA Netw Open. 2023;6(11):e2342741. doi:10.1001/jamanetworkopen.2023.42741 Introduction Long COVID, also known as post–COVID-19 condition (PCC), refers to a range of symptoms that may persist for weeks…[...]

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Neurological manifestations of post-acute sequelae of COVID-19: which liquid biomarker should we use?

Dominique Comeau1† Mykella Martin2† Gilles A. Robichaud3,4,5 Ludivine Chamard-Witkowski2,6*1Dr. Georges-L. Long COVID syndrome, also known as post-acute sequelae of COVID-19 (PASC), is characterized by persistent symptoms lasting 3–12 weeks post SARS-CoV-2 infection. Patients suffering…[...]

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